NH-acidities and Hammett correlation of 3-para substituted phenyl-1,2,4-oxadiazol-5(4H)-ones and 1,2 λ 43,5-oxathiadiazole 2-oxides in nonaqueous media

Authors : Nedime DÜRÜST, Yaşar DÜRÜST, Emine Özge GÖZLÜKAYA

Pages : 56-62

Doi:10.3906/kim-1303-46

View : 16 | Download : 11

Publication Date : 0000-00-00

Article Type : Research Paper

Abstract :NH acidities of some 3-insert ignore into journalissuearticles values(p-substitutedphenyl);-1,2,4-oxadiazol-5insert ignore into journalissuearticles values(4H);-ones and 4-insert ignore into journalissuearticles values(p-substitutedphenyl);-1,2 l43,5-oxathiadiazole 2-oxides were determined in methanol by means of potentiometric titration with sodium methoxide. pKa values of the title compounds calculated from the potentiometric data were interpreted on the basis of structural effects caused by para-substituted groups on the phenyl ring by plotting pKa values versus Hammett sp+ constants, which gave excellent linear correlations.
Keywords : Potentiometry, oxadiazol 5 4H, one, oxathiadiazol 2 oxide, linear Hammett correlation