Factors Affecting Perioperative Period Renal Function in Nephrectomies

Authors : Meryem ONAY, Sema ŞANAL BAŞ, Gizem KURADA, Ata ÖZEN, Ebru KARAKOÇ, Birgül YELKEN

Pages : 366-372

Doi:10.20515/otd.1236019

View : 103 | Download : 127

Publication Date : 2023-05-23

Article Type : Research Paper

Abstract :Patients who have had a nephrectomy usually have a history of renal dysfunction or are at risk for kidney failure due to tissue loss during surgery. In this study, our aim was to evaluate the factors affecting acute renal function in nephrectomy surgeries under general anesthesia. Demographic data of patients, case type, surgery type, duration of anesthesia, intraoperative lactate level, and postoperative complications of patients who underwent nephrectomy in our clinic were reviewed. Renal function was compared with urea, creatinine and estimated glomerular filtration rate insert ignore into journalissuearticles values(eGFR); levels in the preoperative insert ignore into journalissuearticles values(2 days before surgery); and postoperative period insert ignore into journalissuearticles values(day 2);. The mean age of the patient was 58.2 ± 13.02 years, duration of anesthesia 166.24 ± 53.01/min, pre-operative eGFR 84.71 insert ignore into journalissuearticles values(67.69-90.0); mL/min/1.73 m2, and postoperative eGFR 65.09 insert ignore into journalissuearticles values(47.91-87.44); mL/min/1.73 m2 were respectively. When the pre- and postoperative renal functions of the patients were compared, the statistically significant results were those of urea insert ignore into journalissuearticles values(p: 0.01);, creatinine insert ignore into journalissuearticles values(p:0.01);, and GFR insert ignore into journalissuearticles values(p:0.01);. The factors affecting GFR decrease were age insert ignore into journalissuearticles values(p:0.01); and case type insert ignore into journalissuearticles values(p:0.01);. Increase in lactate levels in the postoperative period compared to the preoperative levels was statistically significant insert ignore into journalissuearticles values(p: 0.01);. The increase in lactate levels was associated with complications insert ignore into journalissuearticles values(p: 0.001);, case type insert ignore into journalissuearticles values(p:0.01); and surgery type insert ignore into journalissuearticles values(p: 0.01);. Conclusions: The incidence of acute renal failure is increasing in nephrectomy surgeries, especially in radical ones. Age and case type are also the most important parameters to be consider.
Keywords : Nefrektomi, Böbrek fonksiyonu, glomerular filtrasyon hızı

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