The Effect Of Metaphyseal Shock Wave Application On The Longitudinal Growth Of Femur: A Rat Model

Authors : Hilal Yağar, Kadir Eren Biçer, Emin Kürşat Bulut, Levent Ediz, Mehmet Ceylan

Pages : 303-308

Doi:10.20515/otd.1502386

View : 6 | Download : 4

Publication Date : 2025-02-27

Article Type : Research Paper

Abstract :There is an idea that extracorporeal shock wave therapy (ESWT) induces increased blood flow and stimulates the physiological process of bone growth on physis. Also, recent studies have shown that ESWT promotes growth plate chondrogenesis and longitudinal bone growth in rabbits. The aim of the study was to investigate the longitudinal growth of femur bone on a rat model after ESWT application on distal metaphyseal region. The present study used the Multimed 2001- ELMED lithotripter designed for urinary stone treatment on thirty immature rats with unclosed physes. Rats were divided into 3 groups consisting of 10 rats in each group. The age of the rats was ranged from 4 to 6 weeks. To the first group, single dose 0.3 mJ/mm2, 1000 shock wave; to the second group single dose 0.7 mJ/mm2, 1000 shock wave; and to the third group 3 doses (1 session weekly period) 0.3mJ/mm2, 1000 shock wave were applied on the right distal femur metaphyseal region under ketamine anesthesia. The left femurs of the same animals were accepted as controls. Radiological measurements were made digitally with the NetCAD 4.0 engineering program. Metaphyseal shock wave application did not affect the longitudinal bone growth in the early stage (p>0.05 in all 3 groups). These results indicate that ESWT applied to the distal metaphysis of the femur had no effect on early longitudinal bone growth based on radiological measurements in rats. Still there is need to further histologic and radiologic studies in this area
Keywords : Anahtar kelimeler: Metafiz, şok dalga tedavisi, longitudinal kemik büyümesi, rat modeli