Predictive value of serum vitamin B12 elevation in acute leukemia

Purpose: In this study; we sought to assess whether elevated vitamin B12 levels during the course of diagnosis might be a predictor of acute leukemias. Materials and method: The study was prepared by retrospectively evaluating the anamnesis and laboratory information of 95 patients diagnosed with acute leukemia insert ignore into journalissuearticles values(AML or ALL);. Those who had any of the conditions clearly known to increase vitamin B12 levels by scanning their anamnesis and laboratory information were not included in the study. Results: In total, it was observed that serum vitamin B12 level at the time of diagnosis was above the normal reference range insert ignore into journalissuearticles values(>771ng/L); in 36% of the patients. In the survival analysis performed to evaluate the effect of high serum vitamin B12 levels on prognosis, no statistically significant difference was found. Conclusion: The data we obtained from this study; shows that high serum vitamin B12 levels may have predictive value for acute leukemia.