A Review on Basic Principles of Mucoadhesion: The Importance of Chitosan as a Mucoadhesive Biopolymer

Authors : Emine Büşra Eker Fidan, Kevser Bal, Saadet Kevser Pabuccuoğlu

Pages : 174-194

Doi:10.46740/alku.1511772

View : 39 | Download : 61

Publication Date : 2025-01-02

Article Type : Review Paper

Abstract :Mucoadhesive polymers have the special functions which lead to adhesion to the mucin/ epithelial surface on the mucus-covered areas in the body such as eye, nose, vaginal and buccal cavities, and GI tract. Therefore, they provide to increase the residence time of the dosage form on the mucosa and to significantly improve the drug administration. Mucoadhesive drug delivery systems containing chitosan and its modified derivatives have many advantages for both local and systemic drug delivery. The goal of this review is to put forward the importance of chitosan as a functionalized mucoadhesive drug delivery system.
Keywords : Mukoadezif Polimerler, Mukoadezif İlaç Taşıma Sistemleri, Kitosan