Determination of antifungal and antimicrobial properties of cream enriched with oils of different medicinal aromatic herbs

Authors : Beril Atmaca, Tuğba Derici, Tolga Duran, Ahmet Atmaca, İbrahim Savaş

Pages : 981-990

View : 27 | Download : 32

Publication Date : 2024-12-28

Article Type : Research Paper

Abstract :The need for therapeutic aromatic herbs is expanding as a result of the emergence of worldwide antibiotic resistance. The literature on the advantages of using infusions or essential oils from these plants is growing. For decades, thyme, sage, and lavender have been popular sources of essential oils and are commonly employed in modern medicine. The goal was to create a cream formulation to facilitate the application of these oils, with the hope that it would be favored in terms of dosage and sensory acceptability. In this case, Lavender, Sage, and Thyme oils were incorporated into cream formulations in advance. Antimicrobial and antifungal actions of essential oils at 5% and 10% ratios were tested for this purpose, and then they were added to the cream formulation, and the same study was repeated. This study also considered stability and consumer acceptance. The findings revealed that lavender essential oil had no impact at any dosage, while sage and thyme essential oils exhibited a selective effect. Lavender and sage showed little heterogeneity in terms of stability in cream formulations; however, thyme oil was deemed unacceptable not only in terms of texture but also in sensory aspects. Clearly, the search for new medications continues, and antimicrobial resistance caused by each new formulation is a global issue. Although resistance to essential oils has not yet been recorded, research is being conducted with the hope that they might offer a solution to global resistance-related illnesses. In this context, the findings of this study, encompassing not only a cream formulation but also data on the use of essential oils with a guiding methodology in the literature, are amenable to clinical investigation.
Keywords : Tıbbi aromatik bitki, Esansiyel yağlar, Krem, Antifungal, Stabilizasyon