Effect of New Water-Soluble Dendritic Phthalocyanines on Human Colorectal and Liver Cancer Cell Lines

Authors : Ebru YABAŞ, Mustafa SÜLÜ, Aykut ÖZGÜR, Yusuf TUTAR

Pages : 689-695

Doi:10.19113/sdufbed.89035

View : 23 | Download : 14

Publication Date : 2017-08-08

Article Type : Research Paper

Abstract :Human hepatocellular carcinoma insert ignore into journalissuearticles values(HepG2); cells and colorectal adenocarcinoma insert ignore into journalissuearticles values(DLD-1); cells were treated with the synthesized water soluble phthalocyanine derivatives to understand the effect of the compounds both on colorectal and liver cancer cells. The compounds inhibited cell proliferation and displayed cytotoxic effect on these cancer cell lines however; the effect of the compounds on healthy control fibroblast cell line was comparatively lower. The compounds can be employed for cancer treatment as anticancer agents.
Keywords : Dendrimer, Anticancer activity, Liver cancer, Colorectal cancer