An Overview of Drug-loaded Contact Lenses

Authors : Heybet Kerem Polat, Nasıf Fatih Karakuyu

Pages : 433-445

Doi:10.22312/sdusbed.1573846

View : 158 | Download : 280

Publication Date : 2025-12-22

Article Type : Review Paper

Abstract :Objective: Within the scope of this review, contact lens types designed for the treatment of ocular diseases, different drug loading methods, and in vitro and in vivo studies performed after drug loading are examined. Result and Discussion: Topical ocular dosage forms have numerous problems, including low bioavailability, poor patient compliance, and potential side effects. Innovative ocular drug delivery systems are being studied to overcome the limitations associated with traditional formulations. One of these systems is drug-loaded contact lenses, which prolong the duration of drug retention in the eye and reduce the occurrence of side effects. Drug-loaded contact lenses have been effectively manufactured using a variety of techniques, including dipping, molecular imprinting, supercritical fluid nanosystems, and vitamin E modification technologies. These techniques have also proved successful in extending the drug\\\'s release period. The preparation techniques, in vitro and in vivo research, and future possibilities for drug-loaded contact lenses are all evaluated in this review of the most recent developments in the treatment of ocular illnesses.
Keywords : Göz, Oküler Sistem, Kontakt Lens, Nanosistem, Vitamin E, Moleküler Baskılama

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