Can inflammatory markers such as lymphocyte to C-reactive protein ratio and hemoglobin, albumin, lymphocyte, and platelet score predict complications after loop ileostomy closure?

Authors : Mevlüt Yordanagil, Hüseyin Bakır, Murat Yıldırım, Namık Özkan, İsmail Okan

Pages : 224-232

Doi:10.21673/anadoluklin.1421211

View : 26 | Download : 35

Publication Date : 2024-05-29

Article Type : Research Paper

Abstract :Aim: This study aims to investigate whether inflammatory biochemical markers such as hemoglobin, albumin, lymphocyte, platelet scores (HALP), and lymphocyte-C-reactive protein ratio (LCR) can predict complications after ileostomy closure. Methods: Eighty-five patients who underwent loop ileostomy closure were included in this retrospective study. Alongside the patient’s demographic data, surgical data, histopathology results, and biochemistry data were recorded. Complications that occurred within the first 30 days after surgery were evaluated using the Clavien-Dindo classification. Inflammation markers such as HALP and LCR were obtained using biochemical parameters. Results: The rate of mild complications (Clavien-Dindo I and II) was 27%, while the rate of severe complications (Clavien-Dindo III and IV) was 12.94%. A statistically significant correlation was found between the development of early complications and levels of albumin, lymphocyte, neutrophil, and C-reactive protein (CRP) (p<0.05). Patients who developed complications had lower mean serum albumin levels and higher mean neutrophil and CRP values. There was a strong correlation between HALP score and LCR and complications in patients (p<0.05). Conclusion: It was concluded that HALP and LCR measured preoperatively could be important predictors of early complications after loop ileostomy closure.
Keywords : Ameliyat sonrası komplikasyonlar, biyokimyasal belirteçler, inflamasyon, loop ileostomi