Mean platelet volume (MPV) levels in subclinical hypothyroidism and its relation to serum lipid levels

Authors : Zafer ERCAN, Mehmet Emin DEMİR

Pages : 234-237

Doi:10.38053/acmj.1077780

View : 26 | Download : 13

Publication Date : 2022-07-26

Article Type : Research Paper

Abstract :Background: Subclinical hypothyroidism (SCH) is a term to define a mild and early thyroid deficiency. Some reports claim SCH has an association with increased cardiovascular disease (CVD), especially in individuals 4 mIU/L TSH levels were labelled for SCH group. Both groups were evaluated for MPV, lipid profiles and epidemiological features. Results: SCH group had higher levels of MPV, total cholesterol (TC) and LDL cholesterol (LDL-C) levels (P<0.05, for each parameter). MPV had a positive correlation to TC and LDL-C (r=0,175 ve p=0,025; r=0,154 and p=0,043). However, a multivariate analysis that rendered the impact of age and gender revealed that SCH had no impact on MPV after adjustment for those parameters gender revealed that SCH had no impact on MPV after adjustment for those parameters (B=0,304; 95% CI: -0,021 – 0,628; p=0,066). Conclusion: SCH patients may have higher levels of MPV. However, age and gender had an impact on MPV levels and we think increased CVD risk in SCH patients is associated with factors other than MPV levels.
Keywords : MPV, lipids, subclinical hypothyroidism