Evaluation of ultrafiltrated fluid overloaded patients: a single center study

Authors : Özgür CAN, Süleyman BAŞ, Gülizar Manga ŞAHİN, Süheyla APAYDIN

Pages : 247-252

Doi:10.38053/acmj.1254921

View : 50 | Download : 69

Publication Date : 2023-07-28

Article Type : Research Paper

Abstract :Aims: Fluid overloaded patients with heart or renal insufficiency have poor quality of life and increased morbidity and mortality. In this study, we aimed to investigate the factors affecting the prognosis in patients who presented with fluid overload and were ultrafiltered. Methods: Three groups of patients were compared: Group 1: Patients with chronic kidney disease and ejection fraction ≤ 40%; Group 2: Patients with chronic kidney disease and ejection fraction > 40%; Group 3: Patients with ejection fraction ≤ 40% but without chronic kidney disease. Patients were also evaluated regarding mortality. Results: Group 1, 2 and 3 consisted of 14, 62 and 16 patients: respectively. There were statistically significant results for 24-hour urine volume insert ignore into journalissuearticles values(p=0.040);, proteinuria insert ignore into journalissuearticles values(p=0.010);, ultrafiltration volume/weight at hospitalization insert ignore into journalissuearticles values(p<0.001);, ejection fraction insert ignore into journalissuearticles values(p<0.001);, left ventricular hypertrophy insert ignore into journalissuearticles values(p=0.040);, uric acid insert ignore into journalissuearticles values(p<0.001);, hemoglobin insert ignore into journalissuearticles values(p<0.001);, dialysis dependency after hospital discharge insert ignore into journalissuearticles values(p<0.001); and mortality insert ignore into journalissuearticles values(p<0.001); when three groups were compared. However, there was no statistically significant result for ultrafiltration volume insert ignore into journalissuearticles values(p=0.100);. Compared to survived patients those who did not survived were significantly older insert ignore into journalissuearticles values(p<0.001);, had lower ejection fraction insert ignore into journalissuearticles values(p=0.010);, creatinine insert ignore into journalissuearticles values(p<0.001);, sodium insert ignore into journalissuearticles values(p=0.020);, ferritin insert ignore into journalissuearticles values(p=0.040);, proteinuria insert ignore into journalissuearticles values(p=0.010);. They also had statistically significantly higher hemoglobin insert ignore into journalissuearticles values(p<0.001);, creatinine clearance insert ignore into journalissuearticles values(p<0.001);, uric acid insert ignore into journalissuearticles values(p<0.001); levels. However, the percentage of patients using loop diuretics at hospitalization insert ignore into journalissuearticles values(p=0.040); was higher in the group who survived. Conclusion: Patients with HF were more prone to hypervolemia and mortality. The ultrafiltration volume/weight at hospitalization and serum uric acid levels were also significantly higher in these patients. Patients with chronic kidney disease had significantly higher proteinuria, creatinine and lower hemoglobin levels. The rate of loop diuretic usage at hospitalization was significantly higher in the survived group.
Keywords : dialysis, heart failure, mortality, ultrafiltration