Biological Activity Evaluation of Scorzonera tomentosa L.

Authors : Gülşen GÜÇLÜ, Nuraniye ERUYGUR, Esra UÇAR, Dilara ÜLGER ÖZBEK, Halil BAL, Aşkın AKPOLAT, Danial KAHRİZİ

Pages : 162-167

Doi:10.19159/tutad.1278795

View : 82 | Download : 98

Publication Date : 2023-07-31

Article Type : Research Paper

Abstract :This study aimed to evaluate the phytochemical components, antimicrobial activity, and antioxidant activity of 80% ethanol extract of Scorzonera tomentosa, an endemic species. The chemical constituents of the ethanolic extract of S. tomentosa was primarily characterized by gas-chromatography-mass spectrometry analysis insert ignore into journalissuearticles values(GC-MS);, ten components were identified. The major component was found as 2-pentanamine insert ignore into journalissuearticles values(35.68%);. When the antioxidant capacity of S. tomentosa was examined, 1,1-diphenyl-2-picrylhydrazyl insert ignore into journalissuearticles values(DPPH); and 2,2-azinobis insert ignore into journalissuearticles values(3-ethylbenzothiazoline-6-sulfonic acid); insert ignore into journalissuearticles values(ABTS); radical scavenging activities were determined to be quite high compared to the reference drug insert ignore into journalissuearticles values(IC50 values; DPPH: 517.0 ± 1.86 µg mL-1; ABTS: 244.8 ± 0.94 µg mL-1; reference drug: 1.313 ± 0.24 µg mL-1);. In addition, according to total phenol content and total flavonoid content analyses, it was determined that the plant is richer in flavonoids. The antimicrobial activity of this species is not at an effective level. More extensive studies with S. tomentosa may allow the plant to be used as a natural antioxidant.
Keywords : Scorzonera tomentosa, Antioksidan kapasite, chemical content, antimicrobial activity