ANTIMICROBIAL ACTIVITY OF EGYPTIAN SIDR HONEY AND ITS SYNERGISTIC ACTION WITH ANTIMICROBIAL AGENTS

Authors : Nageh OMRAN, Mostafa HASSAN, Mohamed ABDELRAHMAN, Abdelaleem DESOKY, Stayed HAMOUDA

Pages : 1-13

Doi:10.31467/uluaricilik.1170635

View : 19 | Download : 10

Publication Date : 2023-05-19

Article Type : Research Paper

Abstract :Determine the in vitro antibacterial potential activity sidr honey produced in upper Egypt against five references bacterial strains insert ignore into journalissuearticles values(Gram positive and Gram negative strains); and its synergistic effect with some antimicrobial agents. Material & Methods: fifteen Sidr honey samples were collected from three Governorates in Upper Egypt. Honey samples were diluted and tested against Staphylococcus aureus, Streptococcus agalactiae, Escherichia coli, Klebsiella pneumoniae and Bacillus cereus by agar dilution method. Post determination of the minimum inhibitory concentration insert ignore into journalissuearticles values(MIC); values, six honey samples were examined for their synergistic action with the ineffective antimicrobial agents. Results: In vitro antimicrobial sensitivity test, all bacterial strains showed multidrug resistance action against the 13 tested antimicrobial agents with high multiple antibiotic resistance insert ignore into journalissuearticles values(MAR); index, it was ≥ 0.38. All Sidr bee honey samples showing antibacterial activity against the five tested references bacterial strains. All Sidr bee honey samples, showed better synergistic effect with all antimicrobial agents against.
Keywords : Mısır Sidr balı, Antimikrobiyal etki, Minimum inhibitör konsantrasyon, Sinerjistik etki