Evaluation of Carotid Artery Intima Media Elasticity in Takayasu Arteritis by Shear Wave Elastography

Authors : Başak Erdemli Gürsel, Sedat Giray Kandemirli, İlker Ercan, Burcu Yağız, Yavuz Pehlivan, Naile Bolca Topal

Pages : 457-462

Doi:10.32708/uutfd.1534895

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Publication Date : 2025-01-12

Article Type : Research Paper

Abstract :This study aimed to evaluate carotid morphology with Ultrasound (US) and arterial stiffness with Shear Wave Elastography (SWE) in TA patients and to compare results with disease activity. We searched the clinical archive and found 41 Takayasu Arteritis (TA) patients with carotid involvement had carotid US and SWE screening. Patients (n=22) with confounding factors that could affect the carotid wall were excluded. Nineteen cases that meet the inclusion criteria and 19 healthy control cases age-sex matched were compared. We evaluated right and left common carotid artery intima-media thickness (IMT) with B-Mode US and wall stiffness with SWE. We also investigated a relationship between disease activation and arterial stiffness. Carotid artery IMT was significantly higher in TA than in the control group (p<0.001). Median stiffness values for the carotid wall in TA were 28.3 kPa and 36.3 kPa on the right and left and in the control group 26.1 kPa and 28.1 kPa, respectively. The left CCA stiffness was significantly higher in the TA than in the control group (p=0.03), whereas the difference in right CCA elasticity did not reach statistical significance. A left CCA cut-off value of 52 kPa reached the highest accuracy with a specificity of 100% and a sensitivity of 36.8% in TA. No significant relationship was found between disease activation and elasticity value. SWE alone is not diagnostic but can be a useful adjunctive modality to gray-scale ultrasound in assessing carotid artery involvement with TA.
Keywords : Takayasu Arteriti, Ultrason, Shear Wave Elastography, Karotis Sertliği, İntima Media Kalınlığı

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