The Clinical Importance of Hematological Parameters In Patients with Pulmonary Thromboembolism Diagnosed in The Emergency Department

Authors : Resmiye Nur Okudan, Fevzi Yılmaz, Serkan Yüksel, Mehmet Karadaş, Adeviyye Karaca, Gizem Ayaz, Ömer Faruk Karakoyun

Pages : 123-129

Doi:10.38175/phnx.989396

View : 251 | Download : 556

Publication Date : 2021-11-01

Article Type : Research Paper

Abstract :Objective: Acute pulmonary embolism (APE) is a highly fatal acute clinical condition. Herein, we aimed to determine the role of blood parameters in the diagnosis and prognostication of APE. Material and Method: This study was conducted retrospectively on patients who had been admitted to our hospital’s emergency department (ED) and diagnosed with APE. Patients with an RV/LV ratio greater than 0,9 on Computed tomography (CT) and hypotension were grouped as massive APE; patients with stable hemodynamics and an RV/LV ratio greater than 0,9 on CT were defined as submissive APE; and patients with stable hemodynamics and an RV/LV ratio smaller than 0,9 on CT were defined as non-massive APE. Results: This study enrolled a total of 200 patients, 82 of which were male (41%) and 118 were female (59%). APE group had a significantly greater D-dimer level than the control group (3.559,5±8.611.3 ng/ml vs 266.6±266.6 ng/ml) (p<0,001). Troponin I levels significantly greater in the patient group than control group (53.3±90 vs 332.9±32,9) (p= 0.013). Conclusion: Analysis of the hematological parameters between the APE subgroups showed that D-Dimer, leukocyte (WBC), neutrophil, lymphocyte, neutrophil to lymphocyte ratio (NLR), and troponin levels were significantly higher in the massive APE group than the sub-massive and non-massive APE groups.
Keywords : Akut pulmoner emboli, Hematolojik Parametreler, Acil Servis