Fibrinogen/Albumin Ratio in Patients with Pulmonary Embolism

Authors : Abdullah Bilge, Ali Duman, Kenan Türkdoğan, Ayhan Aköz

Pages : 67-70

Doi:10.38175/phnx.1202390

View : 281 | Download : 279

Publication Date : 2023-07-01

Article Type : Research Paper

Abstract :Objective: Pulmonary embolism is associated with a high mortality rate when it is not diagnosed emergently. Our aim was to investigate the relationship between the fibrinogen/albumin ratio and pulmonary embolism. Material and Method: Patients who were suspected to have pulmonary embolism and who underwent routine blood testing to initiate the diagnostic process were included in this prospective study. Their fibrinogen and albumin values were evaluated. Results: A total of 130 patients were included in the study. Pulmonary embolism was detected in 71 (54%) of the patients. Of those, 7 (9.9%) were subsegmental, 50 (70.4%) were segmental, and 14 (19.7%) were massive pulmonary. The fibrinogen/albumin ratio of the subjects in the control group was 99.1 (75.2–167.9), whereas the fibrinogen/albumin ratio in the pulmonary embolism group was 151 (125.1–220.5), significantly higher than the control value (P < 0.001). When ROC analysis was performed in the pulmonary embolism group, the fibrinogen/ albumin ratio was found to be a significant predictive factor (AUC: 0.724; 95% CI = 0.635–0.814; P < 0.001). When the fibrinogen/albumin ratio was 119.3, the sensitivity was 77.5%, and specificity was 61.0%. Conclusion: Fibrinogen levels and fibrinogen/albumin ratio were significantly higher in patients with pulmonary embolism.
Keywords : Pulmoner emboli, fibrinojen albümin oranı, ortalama trombosit hacmi