Frequency of spondyloarthropathy in patients with end-stage chronic renal failure and receiving renal replacement therapy (hemodialysis)

Authors : Uğur ÖZDEMİR, Derya KAŞKARİ, Ahmet Eftal YÜCEL

Pages : 6-10

Doi:10.20492/aeahtd.1088143

View : 29 | Download : 11

Publication Date : 2023-04-30

Article Type : Research Paper

Abstract :Objectives: Destructive spondyloarthropathy insert ignore into journalissuearticles values(dSpA); occurs due to inflammatory destruction of axial joints due to beta2-microglobulin insert ignore into journalissuearticles values(beta2-M); accumulation in patients with end-stage renal disease insert ignore into journalissuearticles values(ESRD); receiving renal replacement therapy insert ignore into journalissuearticles values(RRT);. This study aimed to investigate the frequency of dSpA in ESRD patients receiving RRT, by the diagnostic criteria sets of inflammatory back pain insert ignore into journalissuearticles values(IBP); and inflammatory classical SpA. Methods: A total of 140 patients were included. The data of the demographic informations, laboratory tests, clinical findings, HLA allele subgroups were collected. Sacroiliac and lateral feet X-rays and if necessary sacroiliac tomography were taken in patients with dSpA related pain. dSpA was investigated according to the Amor and ESSG criteria sets. Results: Fifty two patients were women insert ignore into journalissuearticles values(37%);. The mean age was 51 ± 15 years. IBP and sacroiliitis were detected in 22 and 28 of the patients, respectively. There was a significant difference according to sacroiliitis and IBP in terms of CRP insert ignore into journalissuearticles values(p=0.028, p=0.043);. dSpA were detected in 21 insert ignore into journalissuearticles values(15%); patients. Presence of HLA-A1 and duration of HD were determined as independent risk factors for dSpA. Conclusions: In the diagnosis of dSpA, the character and inflammatory origin of the pain and inflammatory markers should be investigated in addition to the radiological criteria.
Keywords : Destürkitif spondiloartropati, hemodiyaliz, beta2 mikroglobulin, böbrek yetersizliği