Cytotoxic and Genotoxic Potential of Hibiscus sabdariffa

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Uşak Üniversitesi Fen ve Doğa Bilimleri Dergisi
Cilt: 9 Sayı: 2
Cytotoxic and Genotoxic Potential of Hibiscus sabdariffa

Cytotoxic and Genotoxic Potential of Hibiscus sabdariffa

Authors : Mualla Dursun, Halil Erhan Eroğlu

Pages : 171-175

Doi:10.47137/usufedbid.1678297

View : 34 | Download : 78

Publication Date : 2025-12-30

Article Type : Research Paper

Abstract :Hibiscus sabdariffa L., also known as Roselle, has widespread use for medicinal and nutritional purposes. It is important to detect its toxic potential due to its beneficial uses in food and beverage, health, cosmetics, etc. The aim of this study was to evaluate the cytotoxic and genotoxic potential of Hibiscus sabdariffa by Allium test. All concentrations and application periods of Hibiscus sabdariffa extracts decreased the mitotic index and increased the chromosomal defects compared to the control. These effects were statistically significant at 0.5 mg/mL (p˂0.05). The mitotic and chromosomal defects can pave the way for the development of genetic diseases such as cancer, as well as leading to the loss of cell functions and death mechanisms such as apoptosis. Therefore, it is important to avoid using the herb in high concentrations.
Keywords : Allium testi, Hibiscus, toksik etki

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