- Van Sağlık Bilimleri Dergisi
- Volume:12 Issue:2
- Determination of Median Values of First Trimester Screening Tests: A Tokat Scale Retrospective Study
Determination of Median Values of First Trimester Screening Tests: A Tokat Scale Retrospective Study
Authors : Muzaffer Katar
Pages : 15-21
View : 49 | Download : 26
Publication Date : 2019-12-29
Article Type : Research Paper
Abstract :Objectives: The aim of this study was to determine the ability of maternal serum plasma protein A insert ignore into journalissuearticles values(PAPP-A); and free beta-human chorionic gonadotropin insert ignore into journalissuearticles values(free ß-hCG); values measured in the first trimester screening test to predict the complications that may develop in later gestational weeks, calculate the median values of these parameters and compare them with those of software we use. Materials and methods: The study included 16-46 years old women who applied to biochemistry laboratory of Tokat Gaziosmanpasa University School of Medicine with gestational ages of 10 weeks and 6 days to 13 weeks and 6 days. The results of 3166 pregnant women were evaluated retrospectively. Results: The mean age of the patients was 27.43 ± 5.46 and their weight was 65.66 ± 13.13 kilograms. Crown rump lengthes insert ignore into journalissuearticles values(CRL); were determined as 60.71 ± 8.56 mm. Free ß-hCG levels were 55.1 ± 132.07 ng / mL and PAPP-A values were 3683.53 ± 2486 mIU / l. Nuchal translucency measurements insert ignore into journalissuearticles values(NT); were determined as 1.38 ± 0.37mm. PAPP-A and Free ß-hCG MoM values were 1.23 ± 0.68 and 1.23 ± 0.88, respectively. New median values of β-hCG were found to be significantly lower than those of the program insert ignore into journalissuearticles values(p <0.05);, while PAPP-A values were significantly higher insert ignore into journalissuearticles values(p <0.05);. Conclusion: The accuracy and performance of first trimester screening tests should be improved. Determination of median values specific to the region and even to the laboratory is now inevitableKeywords : free ß hCG, PAPP A, Double screening test
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