IMPACT OF PLANT METABOLITES IN GLUCOSE METABOLISM FOR REGULATION OF BLOOD GLUCOSE LEVEL IN DIABETES: AN EXCLUSIVE UPDATE

Authors : Pulak Majumder, Amrutanand Tripathy, Swathi K B

Pages : 498-518

Doi:10.33483/jfpau.1472409

View : 101 | Download : 128

Publication Date : 2025-05-19

Article Type : Review Paper

Abstract :Objective: To explore the molecular targets of plant chemicals and their role in regulating hyperglycemia, providing insights into potential strategies for developing new treatment for this condition. Result and Discussion: Understanding the biochemical pathways involved in sugar regulation is crucial for developing treatments for conditions such as hyperglycemia. Phytochemicals derived from plants have shown promise in regulating blood sugar levels through various molecular targets. By targeting specific enzymes and pathways involved in glucose metabolism, these phytochemicals offer potential therapeutic benefits for managing hyperglycemia. Plant chemicals have demonstrated the ability to influence key enzymes and pathways in glucose metabolism. Phytochemicals have been found to modulate glycolysis, the Krebs cycle, and gluconeogenesis, offering the potential for regulating blood sugar levels. Additionally, these plant extracts have shown effects on processes such as cholesterol synthesis, glycogen synthesis and degradation, carbohydrate metabolism and absorption, as well as insulin production and release. The diverse impact of these medicinal plants on multiple physiological processes highlights their potential to address hyperglycemia through a multi-faceted approach. In this review, we will further explore the molecular targets and mechanisms of action of these plant chemicals, which can provide valuable insights for developing novel treatments for hyperglycemia.
Keywords : Biyokimyasal yolaklar, diyabet, fitokimyasallar, tıbbi bitkiler

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