BCG Vaccine and New Tuberculosis Vaccines Against Mycobacterium tuberculosis: A review

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Aurum Journal of Health Sciences
Volume:2 Issue:2
BCG Vaccine and New Tuberculosis Vaccines Against Mycobacterium tuberculosis: A review

BCG Vaccine and New Tuberculosis Vaccines Against Mycobacterium tuberculosis: A review

Authors : Özgül KISA

Pages : 141-153

View : 88 | Download : 10

Publication Date : 2020-05-31

Article Type : Review Paper

Abstract :Mycobacterium tuberculosis insert ignore into journalissuearticles values(M. tuberculosis); causes tuberculosis insert ignore into journalissuearticles values(TB); which is a serious infectious disease. Bacteria are spread from person to person through tiny droplets released into the air via sneezing and coughing. Despite global efforts to control TB, the disease is the second most common cause of death after Acquired Immune Deficiency Syndrome insert ignore into journalissuearticles values(AIDS);. Currently, Bacillus Calmette-Guérin insert ignore into journalissuearticles values(BCG); vaccine is used to prevent tuberculous meningitis and miliary disease, particularly in young children, but its protective efficacy is variable in adults. Therefore, there is an urgent need for the development of alternative TB vaccines. Recently, new TB vaccine development efforts have been advanced in different clinical studies. Most of these vaccines are live-attenuated or recombinant mycobacterium, live viral vector-based, and protein/adjuvant vaccines. This review explains the recapitulation of the current status of new TB vaccines updated with scientific literature references.
Keywords : Mycobacterium tuberculosis, new vaccines, clinical studies, BCG, review

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