Total fertilization failure in intracytoplasmic sperm injection: a retrospective comparative study

Authors : Hasan İNAL, Zeynep OZTURK INAL

Pages : 168-176

Doi:10.17826/cumj.1221276

View : 18 | Download : 18

Publication Date : 2023-03-31

Article Type : Research Paper

Abstract :Purpose: The aim of this study was to evaluate total fertilization failure insert ignore into journalissuearticles values(TFF);, embryo transfers following TFF cycles, and recurrent TFF, and to define the factors that might cause TFF. Materials and Methods: Cycles that resulted in TFF insert ignore into journalissuearticles values(group 1, n=109);, embryo transfers after TFF cycles insert ignore into journalissuearticles values(group 2, n=30);, and cases of recurrent TFF insert ignore into journalissuearticles values(group 3, n=15); were evaluated retrospectively. Results: Peak estradiol was higher in group 2 than other groups, and the rate of sperm morphology below 4% was lower in group 2 when compared to groups 1 and 3. The total numbers of retrieved oocytes insert ignore into journalissuearticles values(5.3±4.1 vs 10.2±1.5 insert ignore into journalissuearticles values(Odds Ratio=1.639; 95% CI 1.267-2.122);); and MII oocytes insert ignore into journalissuearticles values(2.9±2.2 vs 6.8±1.8 insert ignore into journalissuearticles values(Odds Ratio=2.218; 95% CI 1.529-3.216);); were significantly higher in embryo transfer cycles when compared to previous TFF cycles. Retrieved and MII oocytes counts were higher in group 2 with a median fertilization rate of 46.42% when compared to groups 1 and 3. Conclusion: With more retrieved and MII oocytes, normal sperm morphology can increase the fertilization rate of ICSI cycles following earlier TFF.
Keywords : infertilite, intrasitoplazmik sperm enjeksiyonu, perinatal sonuçlar, total fertilizasyon başarısızlığı