Relationship between vitamin D and magnesium

Authors : Semih KALYON

Pages : 402-408

Doi:10.17826/cumj.1184194

View : 105 | Download : 230

Publication Date : 2023-07-02

Article Type : Research Paper

Abstract :Purpose: Vitamin D is a steroid hormone that plays an essential role in healthy bone structure. Magnesium plays a role as a cofactor for enzymes in vitamin D synthesis and degradation. The study aims to determine whether there is also accompanying magnesium deficiency, in patients with vitamin D deficiency or insufficiency. Materials and Methods: Patients over the age of 18 who applied to the internal medicine outpatient clinic of our tertiary center for any reason between 01.10.2018 and 01.10.2020 were screened and patients whose serum glucose, ALT, creatinine, Vitamin D, and magnesium values were all present at the same time were selected. Pregnant and lactating women, patients with malignancy, chronic renal failure, hyperparathyroidism, or hypoparathyroidism, and patients under vitamin D or magnesium supplementation were excluded. Age, gender, and laboratory data of the included patients were recorded. Results: A total of 5982 patients, 1197 male and 4785 female, were included in this study. The mean age of the cases was 42 years. There was no statistically significant relationship between Vitamin D values and magnesium or glucose levels However, there was a statistically significant relationship between serum vitamin D levels and age and serum creatinine and ALT levels. Both vitamin D and magnesium levels in women were found to be statistically significantly lower than in men. Conclusion: Since there was no relationship between Vitamin D and magnesium levels, there is no need for a routine magnesium examination to be performed in patients with vitamin D deficiency or insufficiency who are planned to take vitamin D therapy.
Keywords : Vitamin D, Magnezyum, Deiyodinaz