Relationship between impulsivity, aggression and blood ghrelin, vitamin D, lipids levels in borderline personality disorder

Authors : Sema BAYKARA, Şahin KARAKAŞ, Şuheda KAYA, Gülay TAŞCI, Selda TELO

Pages : 644-653

Doi:10.17826/cumj.1243820

View : 55 | Download : 139

Publication Date : 2023-07-02

Article Type : Research Paper

Abstract :Purpose: This study aimed to investigate the correlations between impulsivity and aggression, and blood ghrelin, lipids, and vitamin D levels in Borderline Personality Disorder insert ignore into journalissuearticles values(BPD);. Materials and Methods: Thirty female patients with BPD and 30 healthy controls were included to the study. Sociodemographic Data Form, Beck Anxiety Inventory insert ignore into journalissuearticles values(BAI);, Beck Depression Inventory insert ignore into journalissuearticles values(BDI);, Barratt Impulsivity Scale Short Form insert ignore into journalissuearticles values(BIS-11-SF);, Buss-Perry Aggression Questionnaire insert ignore into journalissuearticles values(BPAQ); were applied. Results: Ghrelin, cholesterol, and triglyceride insert ignore into journalissuearticles values(TG); levels were higher in BPD patients insert ignore into journalissuearticles values(p=0.013, p=0.042, p=0.019, respectively);; however, there was no significant difference between the groups based on vitamin D, High-density lipoprotein insert ignore into journalissuearticles values(HDL); and Low-density lipoprotein insert ignore into journalissuearticles values(LDL); levels. There was no correlation between ghrelin, and lipid and vitamin D levels. The BIS-11 and BPAQ scores were higher in BPD group. A positive correlation was determined between ghrelin and BIS-11 scores. A positive correlation was found between vitamin D and ‘anger’ subscale score of BPAQ. A negative correlation was identified between triglyceride and the ‘verbal aggression’ subscale score of BPAQ. Conclusion: BPD is a disorder with several hospital admissions, frequent comorbid conditions, problematic social relationships, and functionality, and the treatment is quite difficult. Regulation of Ghrelin, vitamin D and lipid levels could assist clinicians in the treatment and clinical follow-up of the disease.
Keywords : Borderline kişilik bozukluğu, impulsif davranış, agresyon, ghrelin, vitamin D, lipitler