Morphometric analysis of adrenal gland in people living with human immunodeficiency virus

Authors : Ayşe Gül Kabakcı, Ferit Kuşcu, Ferhat Can Pişkin, Yeşim Taşova, Memduha Gülhal Bozkır

Pages : 159-169

Doi:10.17826/cumj.1391874

View : 36 | Download : 84

Publication Date : 2024-03-29

Article Type : Research Paper

Abstract :Purpose: We aimed to evaluate the effect of Human Immunodeficiency Virus (HIV) infection on adrenal gland morphometry according to age, gender, body weight, survival status and CD4/CD8 parameters. Materials and Methods: In this study, the CT archives (130 men and 30 women) of 160 people living with HIV infection who had imaging for any reason between 2008 and 2020 were scanned. Ages, years of follow-up, body weights, heights, CD4 and CD8 values of people with human immunodeficiency virus were obtained simultaneously with the CT examinations of the people. Anatomical measurements, adrenal gland shapes, length, corpus thickness, medial thickness, lateral thickness, distance to next anatomical structures (esophagus, vertebral column, vena cava inferior, aorta abdominalis and diaphragm) were evaluated. Results: In our study, the average age was 40.29±13.19 (male: 39.78±12.50, female: 42.53±15.88), body weight and height were respectively 67.04±18.10 kg 157.92±6.21 cm in women and 77.06±12.93 kg, 171.67±8.97 cm in men, living with HIV infection were included. As anatomical measurements, the length, corpus thickness, medial crus thickness, lateral crus thickness, distance to the esophagus, columna vertebralis, vena cava inferior, aorta abdominalis and diaphragm of the adrenal gland were found respectively on the right; 4.77±1.70 cm, 3.59±1.23 mm, 2.76±0.83 mm, 2.79±0.87 mm, 3.21±1.21 cm, 1.45±0.85 cm, 0.92±0.57 cm, 2.41±0.65 cm, 1.57±0.84 cm and on the left; 5.78±2.8 cm, 3.77±1.43 mm, 3.38±1.17 mm, 2.92±1.06 mm, 3.10±1.26 cm, 2.11±0.7 cm, 4.10±0.83 cm, 0.90±0.45 cm, 1.21±0.73 cm. The most common adrenal gland type was recorded as Y. Additionally, the mean values of CD4 and CD8 were found to be 322.66±309.35 and 1024.48±930.15, respectively. Conclusion: Some anatomical measurements of the adrenal gland of people living with HIV can be affected by age, gender, body weight, survival status and CD4/CD8 parameters.
Keywords : Adrenal bez, adrenal yetmezlik, anatomi, insan immün yetmezlik virüsü