Clinical characteristics and factors associated with functional outcome in patients with Guillain Barré syndrome

Authors : İlkin İyigündoğdu, Eda Derle, Zeynep Kaya, Güven Girgin, Sevgi İkbali Afşar, Oya Ümit Yemişçi, Berna Alkan, Seda Kibaroglu, Ülkü Sibel Benli

Pages : 460-470

Doi:10.17826/cumj.1431880

View : 59 | Download : 93

Publication Date : 2024-06-30

Article Type : Research Paper

Abstract :Purpose: We aimed to evaluate the clinical characteristics of Guillain Barré syndrome (GBS) patients retrospectively and identify the prognostic factors associated with worse outcome at discharge and at the end of the first month in patients with GBS. Materials and Methods: Patients who were followed up with the diagnosis of GBS were evaluated retrospectively. Demographic characteristics of the patients, cerebrospinal fluid examinations, treatment regimens, Medical Research Council (MRC) and Hughes Motor Scale (HMS) scores were recorded and HMS ≥3 was accepted as associated with poor prognosis in patients. SPSS version 25 program was used in the statistical analysis of the data. p<0.05 was found to be statistically significant. Results: After the exclusion criteria 82 patients were evaluated in this study. The mean age of patients was 56.88±17.14 years and 57.3% (n=47) of the patients were male. The most common neurological finding was paresis in the lower extremities (n=67, 81.7%) followed by paresis in the upper extremities (n=48, 58.5%). Presence of paresis in lower extremities, the median of the duration of hospitalization and the mean of MRC scores at admission were statistically significantly different in patients with poor prognosis at discharge and at the end of the first month. Conclusion: Since patients may have different clinical and electrophysiological characteristics between countries, we believe that there is a need for various publications from different countries to collect information related to the clinical features and prognosis of patients, and we think our study will contribute to these data.
Keywords : Guillain Barré sendromu, prognoz, Hughes Motor Skalası