Molecular Basis of Alzheimer Desease

The prevalence of Alzheimer`s disease ranges from 3 -11% in persons over ages 65 years. It is a significant problem about aging. It is reported that most of 70 to50% of demantias is Alzheimer`s disease in Western Europe   and the United States   according to   Japan moreover Russia researchers have been reported that there is more multi infarct demantias. In addition, the incidence of the disease and epidemiological studies   have   not still determine   yet in Turkey.A great deal of research has been conducted recently; and the knowledge of the clinical characteristics, neuropathology, genetics, and possible treatments has accumulated. In this review, these improvements will be summarised.   Key Words: Alzheimer disease, clinical carecteristics, neuropathology, genetics, treatments