A Fourier Transform Infrared Spectrophotometry Method Used For Oseltamivir Determination in Pharmaceutical Formulations

Authors : Y ABOULENEIN, Andrei BUNACIU, Sultana NITA, Serban FLESCHIN, Zeynep AYDOGMUS

Pages : 631-634

View : 19 | Download : 21

Publication Date : 2012-02-06

Article Type : Other Papers

Abstract :A Fourier transform infrared insert ignore into journalissuearticles values(FT-IR); spectrometric method was developed for the rapid, direct measurement of oseltamivir phosphate insert ignore into journalissuearticles values(OP); in pharmaceutical formulations. Conventional KBr-spectra were compared for best determination of the active substance in pharmaceutical preparations. The Beer-Lambert law and two chemometric approaches, partial least squares insert ignore into journalissuearticles values(PLS); and principal component regression insert ignore into journalissuearticles values( PCR +); methods, were used in data processing.   Key words : FT-IR analysis, oseltamivir, chemometric methods, pharmaceutical analysis.  
Keywords : FT IR analysis, oseltamivir, chemometric methods, pharmaceutical analysis