- Hitit Medical Journal
- Volume:5 Issue:3
- Effect of Barley Grass on Antioxidant Capacity and DNA Damage in Diabetic Rats
Effect of Barley Grass on Antioxidant Capacity and DNA Damage in Diabetic Rats
Authors : Arzu COMBA, Leyla MİS, Devrim SARIPINAR AKSU, Yıldıray BASBUGAN, Bahat COMBA
Pages : 149-155
Doi:10.52827/hititmedj.1281145
View : 48 | Download : 36
Publication Date : 2023-10-10
Article Type : Research Paper
Abstract :Objective: Worldwide, phytotherapy methods acquire great importance, and studies in this field are increasing their importance each day. This study, it was aimed to examine total antioxidant, oxidant status, oxidative DNA damage, glucose and hemoglobin A1c levels and the effects of barley grass juice on these parameters in rats with diabetes mellitus. Material and Method: Four groups were formed for the study and 6 male rats weighing 250-350 g were used in each group. Control Group; physiological saline was injected via intraperitoneal., Diabetic Group; created using streptozotocin, Barley Grass Group; Barley grass juice insert ignore into journalissuearticles values(3 ml/rat/day); was given orally for 4 weeks, Diabetic and Barley Grass Group; was injected streptozotocin and barley grass juice was given by oral for 4 weeks. Results: It was determined that barley grass juice decreased blood sugar, glucose, hemoglobin A1c, total oxidative status and oxidative stress index values, increased total anti-oxidative status value, and body weights in streptozotocin-induced diabetes. In addition, it was determined that the addition of barley grass juice provided a significant protective effect and improvement in these parameters. Conclusion: Based on these findings, we can say that barley grass juice has an antidiabetic-antioxidant effect and weight gain in diabetes mellitusKeywords : arpa çimi, diabet, glukoz, HbA1c, TAS TOS, DNA hasarı
ORIGINAL ARTICLE URL