Optimization of the Schiff-Base Reaction of Acetylacetone with Biogenic Amines

Authors : Bediha AKMESE, Asan ADEM

Pages : 79-83

Doi:10.17350/HJSE19030000052

View : 20 | Download : 12

Publication Date : 2017-06-30

Article Type : Research Paper

Abstract :I n this work, optimum conditions for the derivatization reaction of biogenic amines histamine, tyramine, putrecine, tryptamine, phenylethylamine, cadaverine, spermidine and spermine with acetylacetone have been determined. In this reaction, the amount of K2HPO4, reaction time, reagent amount, solvent choice and solvent amount were optimized. As a result of this study, optimum conditions were determined as amount of K2HPO4 2 g, reaction time 20 min, amount of acetylacetone 1 mL, solvent methanol and amount of solvent 10 mL
Keywords : Biogenic amines, Acetylacetone, Derivatization, Schiff Base