Preparation, Characterization and Evaluation of Some New Amides as Antimicrobial Agents

Authors : Şükriye ÇAKMAK, Aysel VEYSİOĞLU

Pages : 345-351

Doi:10.17350/HJSE19030000204

View : 17 | Download : 9

Publication Date : 2020-12-31

Article Type : Research Paper

Abstract :The some new amide derivatives 1insert ignore into journalissuearticles values(a-c); and, 2d were synthesized by the two-step N-acylation of 4-nitroaniline or heterocyclic amine derivatives with acyl chlorides. All of the products were determined using 13C NMR, 1H NMR, FT-IR spectroscopies and elemental analysis. Antimicrobial activities of the molecules were evaluated against various bacterial and fungal species. The results show that the some new compounds exhibit good antibacterial and antifungal activities.
Keywords : Amides, Secondary Amides, N Acylation, Antimicrobial Activity, Characterization