Effects of Nutrient-Gene Interactions on Metabolic Diseases

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International Journal of Life Sciences and Biotechnology
Cilt: 8 Sayı: 3
Effects of Nutrient-Gene Interactions on Metabolic Diseases

Effects of Nutrient-Gene Interactions on Metabolic Diseases

Authors : Rumeysa Yıldırım, Sevgi Maraklı

Pages : 226-231

Doi:10.38001/ijlsb.1662907

View : 95 | Download : 216

Publication Date : 2025-12-23

Article Type : Review Paper

Abstract :Metabolic diseases are major global health problems caused by genetic predisposition and nutritional factors. Advances in nutrigenomics have enabled the development of nutritional strategies by revealing the effects of nutrients on gene expression. This review mentions different investigations related to the role of nutrient-gene interactions in metabolic diseases including obesity, diabetes, cancer, and non-alcoholic fatty liver disease. The findings showed that secondary metabolites, macronutrients, and micronutrients can influence diseases by regulating gene expressions. Understanding the complex interactions between nutrients and genes will contribute to developing disease prevention and treatment strategies with fewer or no side effects.
Keywords : cancer, diabetes, nutrigenomics, nutrigenetics, non-alcoholic fatty liver disease, obesity

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