Antioxidant, Enzyme Inhibitory and Calcium Oxalate Anti-crystallization Activities of Equisetum telmateia Ehrn.

Authors : Turgut TAŞKIN, Beyza YILMAZ, Ahmet DOĞAN

Pages : 181-191

Doi:10.21448/ijsm.706514

View : 20 | Download : 15

Publication Date : 2020-09-15

Article Type : Research Paper

Abstract :Equisetum L. is the only genus of the Equisetaceae family, which commonly known as horsetails, in English and atkuyruğu or kırkkilit in Turkish. In traditional medicine, Equisetum telmateia Ehrh. is used in diseases of the urinary system, such as pyelonephritis, prostatic hypertrophy, and cystitis. Besides, this species is known to be used by humans to treat kidney stones or kidney sand. The extracts were obtained from the aerial parts of the E. telmateia using three different extraction methods insert ignore into journalissuearticles values(maceration, Soxhlet, ultrasonic bath); and their antioxidant insert ignore into journalissuearticles values(ABTS, CUPRAC);, anti-urease and anticholinesterase activities were examined. Also, calcium oxalate anti-crystallization activity of Soxhlet methanol extract showing strong antioxidant activity was determined. Soxhlet methanol extract exhibited stronger ABTS radical scavenging insert ignore into journalissuearticles values(0.0676 mM Trolox/mg extract); and cupric ion reducing/antioxidant insert ignore into journalissuearticles values(4.351 mM Trolox/mg extract); activity than other extracts. Soxhlet methanol insert ignore into journalissuearticles values(65.528%); and maceration methanol insert ignore into journalissuearticles values(61.965%); extracts showed the strongest anticholinesterase activity. In the anti-urease assay, it was found that Soxhlet petroleum ether extract insert ignore into journalissuearticles values(15.302%); had the highest anti-urease activity. Furthermore, the data obtained showed that the Soxhlet methanol extract had high efficacy in the nucleation and aggregation phase of calcium oxalate crystals. These results prove that Soxhlet methanol extract has antioxidant, anticholinesterase and anti-crystallization capabilities. Therefore, this extract can be used in the future as an antioxidant and anticholinesterase agent as well as the treatment and / or prevention of stone formation.
Keywords : Equisetum telmateia, Anti urease, Anticholinesterase, Anti crystallization