Comprehensive Study on BeeBread: Palynological Analysis, Chemical Composition, Antioxidant and Cytotoxic Activities

Authors : Gökhan DERVİŞOĞLU, Duygu Nur ÇOBANOĞLU, Sedat YELKOVAN, Davut KARAHAN, Yusuf ÇAKIR, Serhat KOÇYİĞİT

Pages : 166-177

Doi:10.21448/ijsm.1066884

View : 56 | Download : 13

Publication Date : 2022-06-15

Article Type : Research Paper

Abstract :Bee bread is a bee product obtained as a result of fermentation of pollen stored by honey bees in the cells of the honeycomb. Palynological analysis, chemical composition, antioxidant activity of bee bread and its cytotoxic effect against human lung carcinoma insert ignore into journalissuearticles values(A549);, human prostate cancer insert ignore into journalissuearticles values(DU 145); and human neuroblastoma insert ignore into journalissuearticles values(SH-SY5Y); cell lines were investigated in this study. 25 plant taxa were identified with palynological analysis. Fatty acids, cyclic, aromatic, phenolic, terpenoid, diterpen and metallic complex structures were seen in GC-MS results. FTIR consequence were compatible with GC-MS results and the structure types of FTIR results were seen in the dominant compounds of GC-MS results. Radical scavenging activity insert ignore into journalissuearticles values(RSA); of bee bread showed inhibition variability between 20.15 ± 0.68% and 93.18 ± 0.44% depending on the concentration. In addition, the EC50 value was measured as 80.08 ± 0.10 mg/mL. Bee bread exhibited moderately cytotoxic effect at all concentrations insert ignore into journalissuearticles values(15.625 - 2000 µg/mL); against A549, DU 145, and SH-SY5Y cell lines. Bee bread can be used in medical fields because of it’s antioxidant and anticancer properties.
Keywords : Bee bread, Palynological analysis, GC MS, FTIR, Antioxidant, Anticancer

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