Virus Imaging Tools

Authors : Beyhan SAREYYÜPOĞLU

Pages : 75-83

View : 18 | Download : 8

Publication Date : 2020-08-29

Article Type : Review Paper

Abstract :Viruses are very small physical particles that can not be observed with a normal microscope. Only the largest virus, the poxvirus can be seen in the light microscope. Other tools are required for a detailed examination of viruses in ultrastructural size. Especially for the last 20 years, these advanced and ongoing tools have been used in the investigation of the biological molecules and biological processes of viruses. With the help of virus imaging tools, viruses can be identified in clinical samples, thereby explaining the detailed life cycle of the virus. Thus, these tools help the creation of new and safe vaccines and antiviral medicine. In this review, electron microscopy insert ignore into journalissuearticles values(EM); tools were given as scanning electron microscopy insert ignore into journalissuearticles values(SEM);, transmission electron microscopy insert ignore into journalissuearticles values(TEM);, cryo-electron microscopy insert ignore into journalissuearticles values(Cryo-EM); since generally used tools based on EM. Besides EM-based tools, X-ray crystallography which is the basis for cryo-EM and atomic force microscopy insert ignore into journalissuearticles values(AFM); that is relatively economic and easy to apply compared to other microscopies were also described.
Keywords : virus, visualisation, equipments