The preventive role of different doses Spirulina platensis on lipid peroxidation and antioxidant status in healthy rats

Authors : Deniz KARAKCI, Nilay SEYİDOĞLU, Oğuz MERHAN, Kadir BOZUKLUHAN

Pages : 90-95

Doi:10.30704/http-www-jivs-net.793250

View : 20 | Download : 10

Publication Date : 2020-12-30

Article Type : Research Paper

Abstract :There are several antioxidant supplements using for reproductivity and life quality, especially herbal ones. Nowadays, herbal antioxidants especially Spirulina platensis has been still interested due to protective role on oxidant antioxidant balance and health. The present study, we aimed to evaluate the effects of different doses of S.platensis on important oxidant molecule MDA insert ignore into journalissuearticles values(TBA, oxidant malondialdeyhde);, and individual antioxidants as GPx insert ignore into journalissuearticles values(glutathione peroxidase);, CAT insert ignore into journalissuearticles values(catalase); and SOD insert ignore into journalissuearticles values(superoxide dismutase); in healthy rats. For this purpose, we used thirty Wistar Albino male rats in three groups: Control, Low Dose Spirulina insert ignore into journalissuearticles values(500 mg kg-1); and High Dose Spirulina insert ignore into journalissuearticles values(1000 mg kg-1);. S.platensis additives were given by oral gavage daily under a long forty five day of trial. At the end of the study, interestingly, all the antioxidants GPx, CAT, SOD and the oxidant MDA lipid peroxidation values were decreased in group high dose Spirulina compared to Control insert ignore into journalissuearticles values(p < 0.05);. In spite of these decreases, testis weights and indexes were increased in group high dose Spirulina compared to Control significantly. The testis weights and indexes evaluated for normal health of animals. It can be considered that due to the excessive protein and antioxidants features of S.platensis, oxidant and antioxidant mechanisms may be changed. However it can be said that Spirulina can compensate the homeostasis and health of animals. It is also considered that the applications and different doses of S.platensis are needed to be assayed for further studies.
Keywords : Antioxidant, Spirulina platensis, rat, testis index