Diversity of Lactococcus garvieae by Genomic Approaches

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Journal of Anatolian Environmental and Animal Sciences
Volume:6 Issue:4
Diversity of Lactococcus garvieae by Genomic Approaches

Diversity of Lactococcus garvieae by Genomic Approaches

Pages : 506-513

View : 43 | Download : 10

Publication Date : 2021-12-31

Article Type : Research Paper

Abstract :Lactococcus garvieae is the Gram-positive cocci bacteria known as the causative agent of infectious systemic disease. It causes fatal hemorrhagic septicemia in mainly cultured fish species, animals, and humans worldwide. Comparative genome analyses provide valuable information about genome identification and unique genomic features. In this study, the available L. garvieae genomes are evaluated by comparative genomics approaches. The results indicated that there are four distinct genetic groups of L. garvieae based on the Average Nucleotide Identity insert ignore into journalissuearticles values(ANI); value. The phylogenetic tree was produced using 16S rRNA sequence has similar genetic variances with the publicly available L. garvieae genome data on NCBI and supports the ANI value. In silico analysis of antimicrobial resistance revealed that each L. garvieae genome groups have unique antimicrobial resistance class genes, even though, all genomes have a common antibiotic-resistant class. Analyzing results of the antimicrobial resistance supports the L. garvieae genetic variations. This extensively comparative approach will provide new insights into the understanding of L. garvieae genomic diversity and antimicrobial resistance.
Keywords : Antibiyotik direnclilik, Karşılaştırmalı genomik, Lactococcus garvieae, Filogenetik ağaç

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