In Vitro Evaluation of Green and Red Propolis Extracts Against Candida spp

Authors : M D FREITAS, G A LOPES, N A OLIVEIRA, B M ALMEIDA, S R L ABREU, R C BASQUES, N S BINDA, S M FIGUEIREDO

Pages : 41-41

View : 9 | Download : 8

Publication Date : 2018-12-08

Article Type : Conference Paper

Abstract :In different countries, propolis has been used as food supplement, which provides organic balance of immune system and as alternative treatment for some diseases 1,2 . Studies have shown that due to the presence of flavonoids in its chemical composition 2 , propolis has anti-inflammatory immunomodulator, antiproliferative, antibacterial, antiviral and antioxidant properties 2,3 . Candidiasis caused by species of Candida genus has high incidence due to the increasing number of immune suppressed people. It has being observed an enhancement of resistance of these fungi to the actual antifungals 3 . In this work ethanol extracts of green insert ignore into journalissuearticles values(GrProp); and red propolis insert ignore into journalissuearticles values(RdProp); were subjected to in vitro assays against six C . albicans ATCC strains and 10 clinical isolates. Minimum inhibitory concentration of extracts was determined. The extracts stood out in relation to the growth inhibition of all ATCC Candida tested, with concentrations varying from 125.0-1000.0μg/mL insert ignore into journalissuearticles values(25% RdProp); and 500-2000μg/mL insert ignore into journalissuearticles values(100% GrProp);. In relation to inhibition of growth of all tested Candida spp., best results were found for extract 25% RdProp insert ignore into journalissuearticles values(125-1000μg/mL); and 100% GrProp insert ignore into journalissuearticles values(500 -2000 µg/mL);. Due to observed anti- Candida activity was inferred that RdProp have potential to be used against candidiasis. Acknowledgements. To Conselho Nacional de Pesquisas insert ignore into journalissuearticles values(CNPq); for financial support insert ignore into journalissuearticles values(Project: 421544/2016-3);
Keywords : Green propolis, Red propolis, In vitro, Candida spp