A Review on The Development, Production Strategies, and Utilization of Monoclonal Antibodies

Authors : Gamze SANLAV, Ömer BEKÇİOĞLU, Yasemin BAŞBINAR

Pages : 197-204

View : 17 | Download : 7

Publication Date : 2020-09-01

Article Type : Research Paper

Abstract :Over the last 20 years, monoclonal antibodies have become the backbone of biological therapeutics for the treatment and diagnosis of several diseases. The rising incidence of cancer and other immunologic diseases promoted the increasing investments of the global pharmaceutical industry in monoclonal antibody development. The R&D has focused on the highest efficacy which is majorly correlated with the antigenbinding specificity and the lowest immunogenicity of monoclonal antibodies. This review aims to provide a brief description and explanation of each stage in the development path of mAbs. Keywords: monoclonal antibodies, industry, cancer
Keywords : monoclonal antibodies, industry, cancer