The cost effectiveness of the respiratory virus panel in childhood febrile neutropenia

Authors : Buket KARA, Gülsüm ALKAN, Kübra ERTAN, Melike EMİROĞLU, Uğur ARSLAN, Hüsamettin VATANSEV, Yavuz KÖKSAL

Pages : 342-346

Doi:10.16899/jcm.1228131

View : 19 | Download : 10

Publication Date : 2023-03-22

Article Type : Research Paper

Abstract :ABSTRACT Objective: The aim of this study is to analyze the clinical utility and cost of the respiratory virus panel test in the febrile neutropenia insert ignore into journalissuearticles values(FN); episode in children undergoing chemotherapy. Material and Method: From 2014 to 2018, 180 episodes of FN in 93 children with cancer were retrospectively analyzed. The patients were divided into those with insert ignore into journalissuearticles values(Group A); and without respiratory virus panel insert ignore into journalissuearticles values(Group B);. The demographic and clinical features and cost analysis of the groups A and B were noted. Results: Of these FN episodes, 46 were in Group A insert ignore into journalissuearticles values(25.5%); and 134 were in Group B insert ignore into journalissuearticles values(74.5%);. We found positivity in 45 insert ignore into journalissuearticles values(97.8%); of 46 episodes in Group A. While modification was required in 14 FN episodes insert ignore into journalissuearticles values(30.4%); in Group A, modification was required in 35 FN episodes insert ignore into journalissuearticles values(26.1%); in group B. The difference was not statistically significant insert ignore into journalissuearticles values(p=0.570);. In Group A, only 5 insert ignore into journalissuearticles values(10.8%); were modified according to the respiratory virus panel. The respiratory virus panel prices were $72.43 insert ignore into journalissuearticles values(interquartile range, $38.8);. The ratio of respiratory virus panel cost to the total cost was 9.67% insert ignore into journalissuearticles values(interquartile range 11.6);. The median total cost of group A was $663.18 insert ignore into journalissuearticles values(interquartile range, 850.1);, while that of group B was $596.24 insert ignore into journalissuearticles values(interquartile range, 723.81);. The difference was not statistically significant insert ignore into journalissuearticles values(p=0.141);. Conclusion: The respiratory virus panel may contribute to the preference of antibiotics by giving rapid results in FN attacks. However, no effect on modification rates was observed, and only a small percentage of patients underwent antibiotic modification according to respiratory virus panel.
Keywords : Febrile neutropenia, respiratory virus panel, children