Single center experience in neuroblastoma, surgical results and complications

Authors : İlknur Banlı Cesur, Zerrin Özçelik, Gunay Ekberli, Begül Yağcı-küpeli

Pages : 238-244

Doi:10.16899/jcm.1699324

View : 128 | Download : 55

Publication Date : 2025-09-30

Article Type : Research Paper

Abstract :Abstract Background/Aims: Neuroblastoma (NB) is an embryonal neuroendocrine tumor of the peripheral nervous system. It is the most common extracranial solid tumor of childhood and the most common in the first year of life.It has a variable course ranging from a benign course to a fatal disease Methods: Forty patients under the age of 18 who underwent surgical resection in our center due to neuroblastoma between January 2012 and December 2021 were included in to the study. Demographic data of the patients, preoperative cross-sectional and functional imaging, surgical procedures, surgical complications and pathological staging were analyzed retrospectively. Results: In this retrospective study, 48 patients were analyzed. Of 48 patients 52.5% were male and 47.5% were female. palpable abdominal mass detected in 82.5% of the patients. 0 patients were neuroblastoma, 10 patients were ganglioneuroblastoma, and 8 patients were ganglioneuromas. Eight patients with ganglioneuroma were excluded from the study. Analysis was performed among 40 patients. Conclusions: NB is heterogeneous in clinical behavior. It is treated by the pediatric surgeon with minimal complications, taking into account the stage of the disease, the age of the patient, and risk factors. Since the tumor originates from the sympathetic nervous system and invades surrounding large vessels and surrounding tissues, aggressive chemotherapy and local regional radiotherapy may be required after surgery. It may be possible to avoid serious complications by customizing the surgery.
Keywords : nöroblastom, , cerrahi, klinik davranış

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