The predictors of complicated acute appendicitis: large unstained cells, gamma-glutamyl transferase, monocyte to platelet ratio, age and gender

Authors : Aziz Ahmet SUREL, Bülent GÜNGÖRER

Pages : 477-481

Doi:10.32322/jhsm.929159

View : 24 | Download : 9

Publication Date : 2021-07-15

Article Type : Research Paper

Abstract :Aim: In this study, we sought to investigate possible biomarkers markers that can preoperatively distinguish complicated and non-complicated acute appendicitis. Material and Method: Patients who underwent appendectomy between February and December 2019 were screened retrospectively. Patients with pathology findings other than appendicitis were excluded. Patients with a confirmed diagnosis of acute appendicitis were categorized as complicated and non-complicated appendicitis for analysis of sociodemographic characteristics, comorbidities and preoperative laboratory parameters. Results: A total of 575 patients were included in the study. Among these, 432 insert ignore into journalissuearticles values(75.1%); were diagnosed with non-complicated appendicitis and 143 insert ignore into journalissuearticles values(24.9%); were diagnosed with complicated appendicitis. The mean insert ignore into journalissuearticles values(SD); age was 34.2±14.2 years. Hypertension, diabetes mellitus and hypothyroidism were the most frequent comorbidities. Age insert ignore into journalissuearticles values(OR, 1.026; p=0.010);, male gender insert ignore into journalissuearticles values(OR, 1.837; p=0.044);, LUC insert ignore into journalissuearticles values(OR: 19.868; p=0.034); and GGT insert ignore into journalissuearticles values(OR: 1.013; p=0.013); were associated with a higher risk of complicated appendicitis. An increase in monocyte to platelet ratio insert ignore into journalissuearticles values(MPR); insert ignore into journalissuearticles values(OR: 0.920; p=0.047); was associated with a lower risk of complicated appendicitis. Conclusion: In patients with acute appendicitis, parameters including age, gender, as well as LUC, GGT and MPR, which are easily available and relatively cheap biomarkers, can be useful to distinguish non-complicated and complicated cases preoperatively.
Keywords : acute appendicitis, appendectomy, large unstained cells