CRP, WBC and monocyte/lymphocyte ratio relation as a preoperative predictive factor for adhesions observed during laparoscopic cholecystectomy

Authors : Doğukan DURAK, Ertugrul Gazi ALKURT, Mehmet Berksun TUTAN

Pages : 686-691

Doi:10.32322/jhsm.952507

View : 32 | Download : 11

Publication Date : 2021-09-05

Article Type : Research Paper

Abstract :Introduction: Inflammation can adversely affect an operation. The ımportant markers of this inflammation are CRP insert ignore into journalissuearticles values(C-reactive peptide);, WBC insert ignore into journalissuearticles values(white blood cell);. Aim: The purpose of this study to predict adhesion related technical difficulties during operation by comparing preoperative CRP, WBC, Monocyte/Lymphocyte ratio and intra-operative adhesion findings. Method: This was a retrospective study. This study includes 116 elective and emergency cholelithiasis cases whose operation performed at Corum Erol Olcok Training and Research Hospital in 2020 and 2021. Adhesions on gallbladder were graded during operation and divided into two groups. Groups graded based on intra-operative findings were compared with preoperative CRP, WBC, and monocyte/lymphocyte ratio. Results: The patients were divided into two groups based on the adhesion grade as Grade 1-2 insert ignore into journalissuearticles values(n=84); and Grade 3-4 insert ignore into journalissuearticles values(n=32);. Average WBC count of Grade 3-4 group was average 11.05 ± 4.45 109 /L and this value was statistically significantly higher insert ignore into journalissuearticles values(p=0.01); than Grade 1-2 group. Average CRP value of Grade 3-4 group was found as 50.91 ± 77.25 mg/L and this value was significantly elevated insert ignore into journalissuearticles values(p 24.5mg/l);, WBC insert ignore into journalissuearticles values(>11.55 109 /L);, monocyte/lymphocyte ratio insert ignore into journalissuearticles values(>0.2693); cut-off values. Conclusion: Preoperative estimation of adhesion grade helps the surgeon considerably. This study shows that high CRP, WBC, and Mo/Ly ratio values can help the estimation of intensity of adhesions and challenges during operation.
Keywords : cholecystectomy, intra operative adhesion, C reactive peptide, white blood cell, monocyte lymphocyte ratio