Choroidal thickness and retinal nerve fiber layer analysis in chronic spontaneous urticaria

Authors : Kürşad Ramazan ZOR, Gamze YILDIRIM BİÇER, Hatice YILDIZ
Pages : 1650-1653
Doi:10.32322/jhsm.1176438
View : 53 | Download : 12
Publication Date : 2022-10-25
Article Type : Research Paper
Abstract :Aim: In this study, we investigated the effects of chronic spontaneous urticaria on the choroid and retinal nerve fiber layer. Material and Method: The patient group consisted of newly diagnosed 54 chronic spontaneous urticaria insert ignore into journalissuearticles values(CSU ); patient and the control group consisted of 54 healthy volunteer. Choroidal and retinal nerve fiber layer insert ignore into journalissuearticles values(RNFL); thickness measurements were performed with Cirrus HD-OCT insert ignore into journalissuearticles values(Carl Zeiss Meditec Inc., Dublin, CA, USA); 30 minutes after pupil dilation with 0,5% tropicamide. Results: In the patient group, nasal choroidal thickness insert ignore into journalissuearticles values(NCT); was 290.11±43.16 μm, subfoveal choroidal thickness insert ignore into journalissuearticles values(SFCT); was 339.17±37.709 μm, temporal choroidal thickness insert ignore into journalissuearticles values(TCT); was 296.00±42.859 μm, mean choroidal thickness insert ignore into journalissuearticles values(MCT); was 308.33±35.923 μm and RNFL thickness was 91.11±7.393 μm. NCT was 248.42±35,742 μm, SFCT 276.56±40.04 μm, TCT 253.69±37.384 μm, MCT 259.50±32,986 μm and RNFL thickness 92.19±8.719 μm in the control group. When we examine the p value, it is seen that both groups are similar to each other in terms of RNFL thickness insert ignore into journalissuearticles values(p=0.326);, while there is a significant thickening in all choroidal regions of patients with CSU, including NCT, SFCT, TCT, MCT insert ignore into journalissuearticles values(p=0.000, p=0.000, p=0.000, p=0.000, respectively);. Conclusion: The choroid is affected in CSU and choroidal thickness can be a noninvasive method that can be used in diagnosis CSU. However, studies of longer disease durations may provide more illuminating information about CSU and choroid and RNFL.
Keywords : Choroidal thickness, chronic spontaneous urticaria, EDI OCT, histamine, retinal nerve fiber layer

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