The association between vitamin D level and ICU mortality in COVID-19 patients: a single center survey

Authors : Sevda ONUK, Esma EREN

Pages : 336-341

Doi:10.32322/jhsm.1198621

View : 26 | Download : 10

Publication Date : 2023-03-27

Article Type : Research Paper

Abstract :Aim: Vitamin D, an immune modulator, may contribute COVID-19 infection. This study aims to assess the relationship between vitamin D value and clinical outcomes insert ignore into journalissuearticles values(need for mechanical ventilation insert ignore into journalissuearticles values(MV); support and intensive care unit insert ignore into journalissuearticles values(ICU); mortality); in critically ill patients diagnosed with COVID-19. Material and Method: This study included critically ill adult patients diagnosed with COVID-19 infection. Serum vitamin D level was analyzed using liquid chromatography mass spectrometry. Vitamin D concentration was classified as normal insert ignore into journalissuearticles values(≥20 ng/mL); and deficiency insert ignore into journalissuearticles values( 0.05);. Conclusion: Approximately 70% of our study sample has below the normal range of serum vitamin D value. Low serum vitamin D concentrations were associated with increased SOFA, creatinine, and troponin concentrations in patients with COVID-19 infection. Vitamin D deficiency was not a predictor of need for MV support and ICU mortality in COVID-19 patients.
Keywords : COVID 19, vitamin D, intensive care unit, mortality