Ultrasonic shear-wave elastography: a novel method for assessing the tumor grade in endometrial cancer: a prospective study

Authors : Emre DESTEGÜL, Burçak ÇAKIR PEKÖZ, Sevtap SEYFETTİNOĞLU, Sevda BAŞ, Fikriye Işıl ADIGÜZEL, Mehmet NARİN

Pages : 987-992

View : 39 | Download : 40

Publication Date : 2023-09-28

Article Type : Research Paper

Abstract :Aims: To evaluate the diagnostic performance of the real time shear-wave elastography in patients with endometrial cancer in terms of tumor grade and myometrial invasion depth preoperatively. Methods: In this prospective observational study, forty-eight women who were diagnosed with endometrioid type endometrium cancer in our gynecologic oncology clinic of a tertiary hospital between September 2020-January 2021 in Turkey. All patients underwent an ultrasonographic shear-wave measurements. Mean shear-wave values were measured from the tumor itself. Mean elasticity values were assessed in terms of tumor grade and myometrial invasion depth. Results: The median [%25-%75] shearwave value of the participants was 29.45kPa insert ignore into journalissuearticles values(5.02-167.21);. Shear-wave value for grade 3 endometrial cancer showed a statistically significant difference compared to grade 1 and 2 shear-wave values insert ignore into journalissuearticles values(p 0.05);. ROC curve analysis showed significant results to determine the myometrial invasion depth and grade 3 endometrial cancer with the mean shear-wave cut-off values of 28.29 kPa and 57 kPa respectively insert ignore into journalissuearticles values(p<0.001);. Conclusion: Real-time shear-wave elastography is a promising tool to predict the grade 3 tumors and deep myometrial invasion in endometrial cancer patients.
Keywords : Endometrial cancer, Shear wave elastography, shear wave, tumor grade, grade 3 endometrial cancer