Skeletal Muscle Mechanics from Hill-Based Muscle Model to Computer Applications: State of the Art Review

Authors : Hamid ASADI DERESHGI, Kasım SERBEST, Sema Nur ŞAHİN, Büşra BALIK

Pages : 27-39

View : 21 | Download : 7

Publication Date : 2021-06-23

Article Type : Review Paper

Abstract :The first studies on muscle mechanics widely accepted in the literature have been known the macroscopic mechanical behavior of skeletal muscle since 1920’s. A. V. Hill and his associates used modern experimental equipment to understand muscle contraction. On the other hand, A. F. Huxley presented cross-bridge models to understand the mechanisms of molecular contraction level, thermodynamics and biochemical experiments on skeletal muscles in the 1950’s. By the 1990’s, computer applications have been used for analysis of muscle mechanics. In this way, somesoftware such as OpenSim, LifeModeler and AnyBody have been developed for only mechanical analysis of musculoskeletal system. In addition, some software developed for general analysis of dynamic systems such as MATLAB, ADAMS, COMSOL and ANSYS can be used for analysis of muscle mechanics. In this study, Hill-type muscle model and Huxley-type cross-bridge model have been explained and computer applications of muscle mechanics have been mentioned.
Keywords : Muscle contraction, muscle force, joint moment, simulation model, finite element model