An evaluation of risk factors for overall complications after curative gastrectomy in gastric cancer patients aged 65 or over

Authors : Serdar Şenol, Mustafa Kuşak, Ahmet Can Sari, Mehmet Emin Kara

Pages : 596-600

Doi:10.47582/jompac.1344042

View : 61 | Download : 94

Publication Date : 2023-10-27

Article Type : Research Paper

Abstract :Aim: The purpose of this study was to identify risk factors for postoperative complications in patients with gastric cancer aged 65 or over. Methods: Data from medical records in our database were reviewed and analyzed retrospectively. Two hundred twenty-nine patients with histologically confirmed gastric cancer underwent curative gastrectomy in our clinic between January 2017 and December 2021. Eighty-eight patients younger than 65 and 21 with previous histories of abdominal surgery, multi-visceral resection, emergency surgery due to perforation, bleeding, or obstruction, 18 with preoperative radiotherapy or chemotherapy were excluded. The remaining 102 patients, aged 65 years or over, were included in the study. Patient characteristics, intraoperative findings, and postoperative complications were evaluated. Results: Postoperative complications with Clavien–Dindo grade ≥ II were observed in 29 patients (28.4%). Univariate analysis showed that the prognostic nutritional index (<45) (odds ratio 0.91; 95% confidence interval, 0.86-0.97; p = 0.004), controlling nutritional status score (≥5) (odds ratio 1.27; 95% confidence interval, 1.09-1.49; p = 0.002), and body mass index (BMI) (≥25 kg/m2) (odds ratio 1.97; 95% confidence interval, 1.00-1.26; p = 0.042) significantly predicted postoperative complications. Multivariate analysis showed that BMI (≥25 kg/m2) (odds ratio 1.18; 95% confidence interval, 1.03-1.34; p = 0.011) significantly predicted postoperative complications. Conclusion: The overall postoperative complication risk among older individuals with gastric cancer who underwent curative gastrectomy was significantly higher among high-BMI patients. Perioperative management with a focus on BMI is important in older patients undergoing elective curative gastrectomy.
Keywords : Ameliyat sonrası komplikasyon, Mide kanseri, Risk faktörü, Yaşlı hastalar