Evaluating the diagnostic accuracy of the 2022 ACR/EULAR classification criteria for giant cell arteritis in routine clinical practice

Authors : Mehmet Nur Kaya, Duygu Tecer, Özlem Kılıç, Sedat Yılmaz

Pages : 194-198

View : 36 | Download : 8

Publication Date : 2025-06-18

Article Type : Research Paper

Abstract :Aims: The 2022 American College of Rheumatology (ACR)/European Alliance of Associations for Rheumatology (EULAR) classification criteria for giant cell arteritis (GCA) were developed to enhance diagnostic accuracy by incorporating advanced imaging modalities and addressing large vessel involvement. This study evaluates the performance of these criteria in routine clinical care. Methods: This study was retrospective and single-center. The results included 25 GCA patients routinely followed at a tertiary rheumatology center from March 2017 to January 2024. The accuracy, sensitivity, specificity, positive and negative predictive values, and area under the receiver operating characteristic (ROC) curve (AUC) of the classification criteria were compared. Results: The sensitivity (92.0%), specificity (92.9%), positive predictive value (92.0%), negative predictive value (92.9%), accuracy (92.4%) and AUC (0.979 (0.925-0.998)) of the 2022 ACR/EULAR classification criteria for GCA were higher than those of the 1990 ACR classification criteria for GCA (88.0%, 85.7%, 84.6%, 88.9% and 86.8%, respectively), and the difference in AUC was statistically significant (0.871 (0.770-0.973), p<0.001). Conclusion: These findings indicate that the 2022 ACR/EULAR criteria significantly improve the sensitivity and maintain adequate specificity compared to the 1990 criteria, making them a valuable tool for diagnosing GCA in clinical practice. The new classification criteria will help to select the right patients and will reduce clinical errors.
Keywords : Dev hücreli arterit, vaskülit, sınıflandırma kriterleri

ORIGINAL ARTICLE URL