Boronic acid functionalized silica microparticles for isolation of flavonoids from Hypericum perforatum

Authors : Onur CETİNKAYA, Hüseyin ÇİÇEK, Şeyda KIVRAK, Gülsen ÇAYAN

Pages : 41-60

Doi:10.18596/jotcsa.307440

View : 51 | Download : 13

Publication Date : 2017-09-01

Article Type : Research Paper

Abstract :We have selectively separated cis- and/or vicinal-diol-containing flavonoids from Hypericum perfaratum insert ignore into journalissuearticles values(HP); by adsorption/desorption using aminophenylboronic acid insert ignore into journalissuearticles values(APBA); functionalized uniform insert ignore into journalissuearticles values(1.6 μm); silica microparticles insert ignore into journalissuearticles values(BASPs); synthesized via the Stöber method. Silica particles were alkylated by its terminal –OH with 3-aminopropyl trimethoxysilane insert ignore into journalissuearticles values(APTS);, glutaraldehyde insert ignore into journalissuearticles values(GA); and APBA. The results from model adsorption studies indicated that these microparticles selectively adsorbed quercetin and rutin but partially apigenin. The antioxidant and antiradical activities of the desorption solution were slightly higher than that of the post-adsorption solution. These results indicated that the BASP selectively adsorbed the cis- and/or vicinal antioxidant and antiradical flavonoids.
Keywords : Antioxidants, Boronic Acid, Free Radical Scavengers, Hypericum Perforatum, Microsphere

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